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Article

Unexpected link between lipooligosaccharide biosynthesis and surface protein release in Mycobacterium marinum.

The Journal of biological chemistry - 8 Jun 2012

van der Woude Aniek D, Sarkar Debasmita, Bhatt Apoorva, Sparrius Marion, Raadsen Susanne A, Boon Louis, Geurtsen Jeroen, van der Sar Astrid M, Luirink Joen, Houben Edith N G, Besra Gurdyal S, Bitter Wilbert

Abstract excerpt

The mycobacterial cell envelope is characterized by the presence of a highly impermeable second membrane, which is composed of mycolic acids intercalated with different unusual free lipids, such as lipooligosaccharides (LOS). Transport across this cell envelope requires a dedicated secretion system for extracellular proteins, such as PE_PGRS proteins, which are specific mycobacterial proteins with polymorphic...

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Identifiers

PMID: 22505711
DOI: 10.1074/jbc.M111.336461
PMCID: PMC3370222

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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