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Article

Prediction of serotonin transporter promoter polymorphism genotypes from single nucleotide polymorphism arrays using machine learning methods.

Psychiatric genetics - 1 Aug 2012

Lu Ake Tzu-Hui, Bakker Steven, Janson Esther, Cichon Sven, Cantor Rita M, Ophoff Roel A

Abstract excerpt

BACKGROUND: The serotonin transporter gene (SLC6A4) and its promoter (5-HTTLPR) polymorphism have been the focus of a large number of association studies of behavioral traits and psychiatric disorders. However, large-scale genotyping of the polymorphism has been very difficult. We report the development and validation of a 5-HTTLPR genotype prediction model. METHODS: The single nucleotide polymorphisms (SNPs)...

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PMID: 22504458
DOI: 10.1097/YPG.0b013e328353ae23

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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