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Article

SMAD4 genetic alterations predict a worse prognosis in patients with pancreatic ductal adenocarcinoma.

Pancreas - 1 May 2012

Singh Puneet, Srinivasan Radhika, Wig Jai Dev

Abstract excerpt

OBJECTIVES: The present study screened the SMAD4 gene in an Indian population of patients with pancreatic ductal adenocarcinoma (PDAC) for the presence of homozygous deletions and mutations. The effect of these genetic alterations on Smad4 protein expression and patient survival was also evaluated. METHODS: This study was conducted on surgically resected paired normal and tumor tissue samples of 25 consecutive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22504380
DOI: 10.1097/MPA.0b013e318247d6af

Genes

SMAD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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