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Article

Radiation promotes colorectal cancer initiation and progression by inducing senescence-associated inflammatory responses.

Oncogene - 30 Jun 2016

Kim S B, Bozeman R G, Kaisani A, Kim W, Zhang L, Richardson J A, Wright W E, Shay J W

Abstract excerpt

Proton radiotherapy is becoming more common as protons induce more precise DNA damage at the tumor site with reduced side effects to adjacent normal tissues. However, the long-term biological effects of proton irradiation in cancer initiation compared with conventional photon irradiation are poorly characterized. In this study, using a human familial adenomatous polyposis syndrome susceptible mouse model, we show...

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Identifiers

PMID: 26477319
DOI: 10.1038/onc.2015.395
PMCID: PMC4837107

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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