Article
Identification of YAP1 as a novel susceptibility gene for polycystic ovary syndrome.
Journal of medical genetics - 1 Apr 2012
Li Tao, Zhao Han, Zhao Xiaoming, Zhang Bo, Cui Linlin, Shi Yuhua, Li Guangyu, Wang Peng, Chen Zi-Jiang
Abstract excerpt
BACKGROUND: A previously reported genome-wide association study (GWAS) of polycystic ovary syndrome (PCOS) in Han Chinese found that several loci of p value around 10e-5 warrant investigation. Replication of the GWAS was applied in this study to determine whether gene YAP1 (yeast associated protein 1) is associated with PCOS. METHODS: An independent set of 1115 PCOS patients and 1137 controls were recruited;...
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