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Article

Virus‑like particles as a vaccine delivery system: Myths and facts

1 Jan 2008

Abstract excerpt

Vaccines against viral disease have traditionally relied on attenuated virus strains or inactivation of infectious virus. Subunit vaccines based on viral proteins expressed in heterologous systems have been effective for some pathogens, but have often suffered from poor immunogenicity due to incorrect protein folding or modification. In this review we focus on a specific class of viral subunit vaccine that mimics...

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PMID: 18438104
DOI: 10.4161/hv.4.1.5559

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