Article
Innovations in structure-based antigen design and immune monitoring for next generation vaccines.
Current opinion in immunology - 1 Aug 2020
Ward Andrew B, Wilson Ian A
Abstract excerpt
The recent explosion of atomic-level structures of glycoproteins that comprise the surface antigens of human enveloped viruses, such as RSV, influenza, and HIV, provide tremendous opportunities for rational, structure-based vaccine design. Several concepts in structure-based vaccine design have been put into practice and are are well along preclinical and clinical implementation. Testing of these designed...
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