Article
Reduced subjective response to acute ethanol administration among young men with a broad bipolar phenotype.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jul 2012
Yip Sarah W, Doherty Joanne, Wakeley Judi, Saunders Kate, Tzagarakis Charidimos, de Wit Harriet, Goodwin Guy M, Rogers Robert D
Abstract excerpt
Elevated lifetime prevalence rates of alcohol use disorders (AUDs) are a feature of bipolar disorder (BD). Individuals at-risk for AUDs exhibit blunted subjective responses to alcohol (low levels of response), which may represent a biomarker for AUDs. Thus, individuals at-risk for BD may exhibit low responses to alcohol. Participants were 20 unmedicated adult males who reported high rates of hypomanic experiences...
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