Article
[The application of a high resolution melting-based genotyping method in studying the association between FTO rs9930506 polymorphism and metabolic syndrome in Beijing population].
Zhonghua nei ke za zhi - 1 Jan 2012
Sun Liang, Wang Xiao-xia, Shi Xiao-hong, Sun Xue-feng, Wang Li-ping, Wang Tian-qi, Tang Lei, Yang Ze
Abstract excerpt
OBJECTIVE: To set up a new method, which is sensitive, low cost, rapid and suitable for clinical application for FTO gene rs9930506 variant genotyping basing on high resolution melting (HRM) platform, and to preliminarily put into practice in susceptibility analysis for metabolic syndrome (MS) in Beijing. METHODS: Unlabelled probe with C3-spacer block specific for rs9930506 variant has been designed according to...
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