Article
High-resolution melting analysis for the rapid detection of an intronic single nucleotide polymorphism in SLC22A12 in male patients with primary gout in China.
Scandinavian journal of rheumatology - 1 Jan 2009
Guan M, Zhang J, Chen Y, Liu W, Kong N, Zou H
Abstract excerpt
OBJECTIVES: The human urate transporter 1 (URAT1, encoded by SLC22A12) was recently identified as the major absorptive urate transporter protein in the kidney responsible for regulating blood urate levels. The present study was designed to investigate the rs893006 polymorphism (GG, GT, and TT) in...
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