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Article

Noise contributions in an inducible genetic switch: a whole-cell simulation study.

PLoS computational biology - 1 Mar 2011

Roberts Elijah, Magis Andrew, Ortiz Julio O, Baumeister Wolfgang, Luthey-Schulten Zaida

Abstract excerpt

Stochastic expression of genes produces heterogeneity in clonal populations of bacteria under identical conditions. We analyze and compare the behavior of the inducible lac genetic switch using well-stirred and spatially resolved simulations for Escherichia coli cells modeled under fast and slow-...

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PMID: 21423716
DOI: 10.1371/journal.pcbi.1002010
PMCID: PMC3053318

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21423716-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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