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Article

Beyond the chemical master equation: Stochastic chemical kinetics coupled with auxiliary processes.

PLoS computational biology - 1 Jul 2021

Lunz Davin, Batt Gregory, Ruess Jakob, Bonnans J Frédéric

Abstract excerpt

The chemical master equation and its continuum approximations are indispensable tools in the modeling of chemical reaction networks. These are routinely used to capture complex nonlinear phenomena such as multimodality as well as transient events such as first-passage times, that accurately characterise a plethora of biological and chemical processes. However, some mechanisms, such as heterogeneous cellular...

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PMID: 34319979
DOI: 10.1371/journal.pcbi.1009214
PMCID: PMC8352075

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