Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Population differences in transcript-regulator expression quantitative trait loci.

PloS one - 1 Jan 2012

Bushel Pierre R, McGovern Ray, Liu Liwen, Hofmann Oliver, Huda Ahsan, Lu Jun, Hide Winston, Lin Xihong

Abstract excerpt

Gene expression quantitative trait loci (eQTL) are useful for identifying single nucleotide polymorphisms (SNPs) associated with diseases. At times, a genetic variant may be associated with a master regulator involved in the manifestation of a disease. The downstream target genes of the master regulator are typically co-expressed and share biological function. Therefore, it is practical to screen for eQTLs by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black People
Share to False Positive Reactions
Share to Genome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to NF-kappa B

Share to Oligonucleotide Array Sequence Analysis

Share to Quantitative Trait Loci

Share to Regression Analysis

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 22479588
DOI: 10.1371/journal.pone.0034286
PMCID: PMC3313997

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Population differences in transcript-regulator expression quantitative trait loci.PMID 22479588Read ↗

Detection and interpretation of expression quantitative trait loci (eQTL).Semantic proximity Read ↗

Genetic association of molecular traits: A help to identify causative variants in complex diseases.Semantic proximity Read ↗

Genetic architecture of transcript-level variation in humans.Semantic proximity Read ↗

Mapping of promoter usage QTL using RNA-seq data reveals their contributions to complex traits.Semantic proximity Read ↗

Efficient and effective control of confounding in eQTL mapping studies through joint differential expression and Mendelian randomization analyses.Semantic proximity Read ↗

ceQTL: A co-expression QTL model to detect a variant that affects transcription factor binding and its target regulationSemantic proximity Read ↗

Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease.Semantic proximity Read ↗

eQTL networks unveil enriched mRNA master integrators downstream of complex disease-associated SNPs.Semantic proximity Read ↗

Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes.Semantic proximity Read ↗

Expression Quantitative Trait loci (QTL) in tumor adjacent normal breast tissue and breast tumor tissue.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.