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Article

Genome-wide association study of treatment refractory schizophrenia in Han Chinese.

PloS one - 1 Jan 2012

Liou Ying-Jay, Wang Hui-Hung, Lee Ming-Ta Michael, Wang Sheng-Chang, Chiang Hung-Lun, Chen Cheng-Chung, Lin Ching-Hua, Chung Ming-Shun, Kuo Chien-Cheng, Liao Ding-Lieh, Wu Ching-Kuan, Liu Chih-Min, Liu Yu-Li, Hwu Hai-Gwo, Lai I-Ching, Tsai Shih-Jen, Chen Chia-Hsiang, Liu Hui-Fen, Chou Yi-Chun, Chen Chien-Hsiun, Chen Yuan-Tsong, Hong Chen-Jee, Wu Jer-Yuarn

Abstract excerpt

We report the first genome-wide association study of a joint analysis using 795 Han Chinese individuals with treatment-refractory schizophrenia (TRS) and 806 controls. Three loci showed suggestive significant association with TRS were identified. These loci include: rs10218843 (P = 3.04 × 10(-7)) and rs11265461 (P = 1.94 × 10(-7)) are adjacent to signaling lymphocytic activation molecule family member 1 (SLAMF1);...

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Identifiers

PMID: 22479419
DOI: 10.1371/journal.pone.0033598
PMCID: PMC3313922

Genes

NFKB1
RIPK4
SLAMF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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