Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ADH1C Ile350Val polymorphism and cancer risk: evidence from 35 case-control studies.

PloS one - 1 Jan 2012

Xue Yao, Wang Meilin, Zhong Dongyan, Tong Na, Chu Haiyan, Sheng Xiaojing, Zhang Zhengdong

Abstract excerpt

BACKGROUND: Alcohol dehydrogenase 1C (ADH1C) is the key enzyme catalyze oxidation of alcohol to acetaldehyde, which plays vital roles in the etiology of various cancer. To date, studies investigated the association between a functional polymorphism in ADH1C, Ile350Val (rs698), and risk of cancer have shown inclusive results. METHODS: A meta-analysis based on 35 case-control studies was performed to address this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Dehydrogenase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Genetic Predisposition to Disease

Share to Neoplasms

Share to Polymorphism, Genetic

Share to Publication Bias

Source

Open in PubMed Open full text

Identifiers

PMID: 22675424
DOI: 10.1371/journal.pone.0037227
PMCID: PMC3366713

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ADH1C Ile350Val polymorphism and cancer risk: evidence from 35 case-control studies.PMID 22675424Read ↗

Further clarification of the contribution of the ADH1C gene to vulnerability of alcoholism and selected liver diseases.Semantic proximity Read ↗

Determination of the effects of alcohol dehydrogenase (ADH) 1B and ADH1C polymorphisms on alcohol dependence in Turkey.Semantic proximity Read ↗

The alcohol dehydrogenase 1C(rs698) genotype and breast cancer: a meta-analysis.Semantic proximity Read ↗

Association between ADH1B and ADH1C polymorphisms and the risk of head and neck squamous cell carcinoma.Semantic proximity Read ↗

Combined effect of ADH1B RS1229984, RS2066702 and ADH1C RS1693482/ RS698 alleles on alcoholism and chronic liver diseases.Semantic proximity Read ↗

Association between alcohol dehydrogenase polymorphisms (rs1229984, rs1573496, rs1154460, and rs284787) and susceptibility to head and neck cancers: A systematic review and meta-analysis.Semantic proximity Read ↗

Meta-analysis of ADH1B and ALDH2 polymorphisms and esophageal cancer risk in China.Semantic proximity Read ↗

Polymorphisms in alcohol metabolizing genes and the risk of head and neck cancer in a Brazilian population.Semantic proximity Read ↗

Alcohol dehydrogenase-1B Arg47His polymorphism is associated with head and neck cancer risk in Asian: a meta-analysis.Semantic proximity Read ↗

Alcohol dehydrogenase genetic polymorphisms, low-to-moderate alcohol consumption, and risk of breast cancer.Semantic proximity Read ↗

Multiple ADH genes are associated with upper aerodigestive cancers.Semantic proximity Read ↗

ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.