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Article

Genetic variations in genes involved in heparan sulphate biosynthesis are associated with Plasmodium falciparum parasitaemia: a familial study in Burkina Faso.

Malaria journal - 4 Apr 2012

Atkinson Alexandre, Garnier Séverine, Afridi Sarwat, Fumoux Francis, Rihet Pascal

Abstract excerpt

BACKGROUND: There is accumulating evidence that host heparan sulphate proteoglycans play an important role in the life cycle of Plasmodium through their heparan sulphate chains, suggesting that genetic variations in genes involved in heparan sulphate biosynthesis may influence parasitaemia. Interestingly, Hs3st3a1 and Hs3st3b1 encoding enzymes involved in the biosynthesis of heparan sulphate are located within a...

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Identifiers

PMID: 22475533
DOI: 10.1186/1475-2875-11-108
PMCID: PMC3364897

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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