Article
Association of interleukin-6 and interleukin-8 with poor prognosis in elderly patients with chronic lymphocytic leukemia.
Leukemia & lymphoma - 1 Sept 2012
Yoon Ju-Yoon, Lafarge Sandrine, Dawe Dave, Lakhi Sunjay, Kumar Rajat, Morales Carmen, Marshall Aaron, Gibson Spencer B, Johnston James B
Abstract excerpt
In population studies, the relative survival in chronic lymphocytic leukemia (CLL) decreases with age. In this study, we demonstrated in a cohort of 189 patients from a CLL clinic that overall survival was lower in the sub-cohort of patients aged ≥ 70 years, but causes of death were similar for all age groups, being progressive CLL, secondary malignancies and infections. As normal individuals age, the plasma...
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