Article
Association of IL-17A and IL-17F gene polymorphisms with chronic hepatitis B and hepatitis B virus-related liver cirrhosis in a Chinese population: A case-control study.
Clinics and research in hepatology and gastroenterology - 1 Jun 2016
Wang Jian, Liu Yanqiong, Xie Li, Li Shan, Qin Xue
Abstract excerpt
BACKGROUND: Interleukin (IL)-17 has been shown to play an important role in tissue inflammation and in the pathogenesis of immune-related liver damage. Genetic variations in IL-17 gene may be associated with the development of hepatitis B virus (HBV) infection. However, literature is scanty regarding their association. METHODS: We conducted a case-control study including 433 subjects (171 healthy controls, 130...
Topics
- Asian People
- Case-Control Studies
- China
- Female
- Genetic Predisposition to Disease
- Genotype
- Hepatitis B virus
- Hepatitis B, Chronic
- Humans
- Interleukin-17
- Liver Cirrhosis