Article
[DNA methylation defects in sporadic and hereditary colorectal cancer].
Gastroenterologia y hepatologia - 1 Jan 2000
Xicola Rosa M, Llor Xavier
Abstract excerpt
DNA methylation is a fundamental epigenetic mechanism in regulating the expression of genes controlling crucial cell functions in cancer development. Methylation defects (both global hypomethylation and hypermethylation of CpG islands) are implicated in colorectal carcinogenesis. Some nutrients h...
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