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Article

Diet and epigenetics in colon cancer

1 Jan 2009

Abstract excerpt

Over the past few years, evidence has accumulated indicating that apart from genetic alterations, epigenetic alterations, through e.g. aberrant promoter methylation, play a major role in the initiation and progression of colorectal cancer (CRC). Even in the hereditary colon cancer syndromes, in which the susceptibility is inherited dominantly, cancer develops only as the result of the progressive accumulation of...

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PMID: 19140224
DOI: 10.3748/wjg.15.257

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