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Article

A PCR-RFLP based protocol for the detection of hepatitis B virus variants in some lamivudine-untreated chronic hepatitis B virus carriers in Pakistan.

Pakistan journal of pharmaceutical sciences - 1 Apr 2012

Tauseef Isfahan, Iqbal Furhan, Rehman Wajid, Ali Muhammad, Qureshi Javed Anver, Aslam Muhammad Assad

Abstract excerpt

Hepatitis B virus (HBV) affects more than 350 million people worldwide and is a leading cause of morbidity and mortality in developing countries like Pakistan. Lamivudine has potential to inhibit hepatitis B virus (HBV) replication but long term lamivudine treatment results in mutations in YMDD region of HBV, making this therapy ineffective. In this study, we have optimized a polymerase chain reaction-restriction...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22459460

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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