Article
Multiple peptidoglycan modification networks modulate Helicobacter pylori's cell shape, motility, and colonization potential.
PLoS pathogens - 1 Jan 2012
Sycuro Laura K, Wyckoff Timna J, Biboy Jacob, Born Petra, Pincus Zachary, Vollmer Waldemar, Salama Nina R
Abstract excerpt
Helical cell shape of the gastric pathogen Helicobacter pylori has been suggested to promote virulence through viscosity-dependent enhancement of swimming velocity. However, H. pylori csd1 mutants, which are curved but lack helical twist, show normal velocity in viscous polymer solutions and the reason for their deficiency in stomach colonization has remained unclear. Characterization of new rod shaped mutants...
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