Article
Cell morphology as a virulence determinant: lessons from Helicobacter pylori.
Current opinion in microbiology - 1 Apr 2020
Salama Nina R
Abstract excerpt
A genetic screen for colonization factors of the human stomach pathogen Helicobacter pylori took a surprising turn with the discovery that some colonization mutants had lost helical cell morphology. Further pursuit of direct morphology screens revealed a large H. pylori 'shapesome' complex consisting of peptidoglycan modification and precursor synthesis enzymes, a cytoskeletal element and putative scaffold or...
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