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Article

Mousing around with caspases and IAPs.

The Biochemical journal - 15 Apr 2012

Rickert Robert C, Salvesen Guy S, Ware Carl F

Abstract excerpt

In a paper in this issue of the Biochemical Journal that questions the role of c-IAP1 (cellular inhibitor of apoptosis 1) in inflammation, new results from the Duckett laboratory remind us of the importance of truly knowing the mice we depend on. It turns out that c-IAP1 is tightly linked to caspase 11 and cannot be segregated by recombination. This disturbing result implies that immune functions ascribed to...

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PMID: 22452818
DOI: 10.1042/BJ20120402

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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