Article
Variation in a locus linked to platelet aggregation phenotype predicts intraparenchymal hemorrhagic volume.
Neurological research - 1 Apr 2012
Appelboom Geoffrey, Piazza Matthew, Bruce Samuel S, Zoller Stephen D, Hwang Brian, Monahan Aimee, Hwang Richard Y, Kisslev Sergey, Mayer Stephan, Meyers Philip M, Badjatia Neeraj, Connolly E Sander
Abstract excerpt
OBJECTIVE: Alteration in platelet aggregation has been shown to promote bleeding and affect outcome after intracerebral hemorrhage (ICH).We investigated the influence of genetic variants of platelet aggregation, and their effects on admission ICH volume and clinical outcome. METHODS: Our prospective study analyzed selected candidate single-nucleotide polymorphisms (SNPs) previously associated with platelet...
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