Article
TRAF3IP2 gene is associated with cutaneous extraintestinal manifestations in inflammatory bowel disease.
Journal of Crohn's & colitis - 1 Feb 2013
Ciccacci Cinzia, Biancone Livia, Di Fusco Davide, Ranieri Micaela, Condino Giovanna, Giardina Emiliano, Onali Sara, Lepre Tiziana, Pallone Francesco, Novelli Giuseppe, Borgiani Paola
Abstract excerpt
BACKGROUND AND AIMS: Genome-wide association (GWA) studies recently identified a novel gene, TRAF3IP2, involved in the susceptibility to psoriasis. Common immune-mediated mechanisms involving the skin or the gut have been suggested. We therefore aimed to assess the role of TRAF3IP2 gene in IBD, with particular regard to the development of cutaneous extraintestinal manifestations (pyoderma gangrenosum, erythema...
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