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Article

Variation in MSRA modifies risk of neonatal intestinal obstruction in cystic fibrosis.

PLoS genetics - 1 Jan 2012

Henderson Lindsay B, Doshi Vishal K, Blackman Scott M, Naughton Kathleen M, Pace Rhonda G, Moskovitz Jackob, Knowles Michael R, Durie Peter R, Drumm Mitchell L, Cutting Garry R

Abstract excerpt

Meconium ileus (MI), a life-threatening intestinal obstruction due to meconium with abnormal protein content, occurs in approximately 15 percent of neonates with cystic fibrosis (CF). Analysis of twins with CF demonstrates that MI is a highly heritable trait, indicating that genetic modifiers are...

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Share to Cystic Fibrosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22438829
DOI: 10.1371/journal.pgen.1002580
PMCID: PMC3305406

Genes

MSRA
CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22438829-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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