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Article

Loci of intestinal distress in cystic fibrosis knockout mice.

Physiological genomics - 15 Jan 2003

Haston Christina K, Tsui Lap-Chee

Abstract excerpt

The strain-dependent survival of cystic fibrosis (CF) knockout mice has been used to map a modifier of CF, Cfm1, in mice and, subsequently, in humans. To identify additional modifiers of the CF phenotype, in this study, the survival of F2 CF mice derived from a cross between congenic C57BL/6J CF and BALB/cJ CF heterozygotes was followed up to 12 wk of age. A genome-wide linkage scan completed in F2 CF mice...

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Share to Intestinal Diseases
Share to Animals, Congenic
Share to Crosses, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cystic Fibrosis

Share to Cystic Fibrosis Transmembrane Conductance Regulator

Share to Mice, Inbred BALB C

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Source

Identifiers

PMID: 12441405
DOI: 10.1152/physiolgenomics.00114.2002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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