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The PSAP Motif within the ORF3 Protein of an Avian Strain of the Hepatitis E Virus Is Not Critical for Viral Infectivity<i>In Vivo</i>but Plays a Role in Virus Release

23 Mar 2012

Abstract excerpt

The ORF3 protein of hepatitis E virus (HEV) is a multifunctional protein important for virus replication. The ORF3 proteins from human, swine, and avian strains of HEV contain a conserved PXXP amino acid motif, resembling either Src homology 3 (SH3) cell signaling interaction motifs or "late domains" involved in host cell interactions aiding in particle release. Using an avian strain of HEV, we determined the...

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PMID: 22438540
DOI: 10.1128/jvi.06711-11

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The PSAP Motif within the ORF3 Protein of an Avian Strain of the Hepatitis E Virus Is Not Critical for Viral Infectivity<i>In Vivo</i>but Plays a Role in Virus ReleasePMID 22438540Read ↗

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