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Article

Muscle function and running activity in mouse models of hereditary muscle dystrophy: impact of double knockout for dystrophin and the transcription factor MyoD.

Muscle & nerve - 1 Apr 2012

Mangner Norman, Adams Volker, Sandri Marcus, Hoellriegel Robert, Hambrecht Rainer, Schuler Gerhard, Gielen Stephan

Abstract excerpt

INTRODUCTION: Mice that lack both the transcription factor MyoD and dystrophin display a more pronounced myopathic phenotype when compared with mdx mice. No data on skeletal muscle function and the impact of exercise training are available. METHODS: Six-month-old wild-type, mdx, myoD(-/-), mdx:myoD(+/-), and mdx:myoD(-/-) mice were randomly assigned to either 4 weeks of voluntary running or sedentary behavior....

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Identifiers

PMID: 22431088
DOI: 10.1002/mus.22318

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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