Article
Rapid, field-deployable method for genotyping and discovery of single-nucleotide polymorphisms associated with drug resistance in Plasmodium falciparum.
Antimicrobial agents and chemotherapy - 1 Jun 2012
Daniels Rachel, Ndiaye Daouda, Wall Mikeal, McKinney Jason, Séne Papa Diogoye, Sabeti Pardis C, Volkman Sarah K, Mboup Souleymane, Wirth Dyann F
Abstract excerpt
Despite efforts to reduce malaria morbidity and mortality, drug-resistant parasites continue to evade control strategies. Recently, emphasis has shifted away from control and toward regional elimination and global eradication of malaria. Such a campaign requires tools to monitor genetic changes in the parasite that could compromise the effectiveness of antimalarial drugs and undermine eradication programs. These...
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