High resolution melting: a useful field-deployable method to measure dhfr and dhps drug resistance in both highly and lowly endemic Plasmodium populations.

doi:10.1186/s12936-017-1811-2

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Article

High resolution melting: a useful field-deployable method to measure dhfr and dhps drug resistance in both highly and lowly endemic Plasmodium populations.

Malaria journal - 19 Apr 2017

Ndiaye Yaye Dié, Diédhiou Cyrille K, Bei Amy K, Dieye Baba, Mbaye Aminata, Mze Nasserdine Papa, Daniels Rachel F, Ndiaye Ibrahima M, Déme Awa B, Gaye Amy, Sy Mouhamad, Ndiaye Tolla, Badiane Aida S, Ndiaye Mouhamadou, Premji Zul, Wirth Dyann F, Mboup Souleymane, Krogstad Donald, Volkman Sarah K, Ahouidi Ambroise D, Ndiaye Daouda

Abstract excerpt

BACKGROUND: Emergence and spread of drug resistance to every anti-malarial used to date, creates an urgent need for development of sensitive, specific and field-deployable molecular tools for detection and surveillance of validated drug resistance markers. Such tools would allow early detection of mutations in resistance loci. The aim of this study was to compare common population signatures and drug resistance...

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PMID: 28420422
DOI: 10.1186/s12936-017-1811-2
PMCID: PMC5395743

Genes

DHFR
DHPS

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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