Article
Population analysis of pharmacogenetic polymorphisms related to acute lymphoblastic leukemia drug treatment.
Disease markers - 1 Jan 2012
Chiabai Marcela A, Lins Tulio C L, Pogue Robert, Pereira Rinaldo W
Abstract excerpt
This study aimed to evaluate in the Brazilian population, the genotypes and population frequencies of pharmacogenetic polymorphisms involved in the response to drugs used in treatment of acute lymphoblastic leukemia (ALL), and to compare the data with data from the HapMap populations. There was significant differentiation between most population pairs, but few associations between genetic ancestry and SNPs in the...
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