Article
Pathobiology of HBV mutants and clinical impact for treatment monitoring.
Expert review of anti-infective therapy - 1 Apr 2009
Si Ahmed Si Nafa, Zoulim Fabien
Abstract excerpt
HBV is the leading cause of liver cancer and frequently leads to cirrhosis and liver failure. The goals of nucleos(t)ide analog treatments are to suppress viral replication to as low as possible, to halt disease progression and to prevent the onset of complications. Due to the mechanism of viral genome persistence, chronic hepatitis B requires long-term therapy that exposes patients to the risk of selection of...
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