Article
A SNP site in pri-miR-124 changes mature miR-124 expression but no contribution to Alzheimer's disease in a Mongolian population.
Neuroscience letters - 25 Apr 2012
Qi Lu, Hu Yi, Zhan Ying, Wang Jing, Wang Bing-Bing, Xia Hong-Fei, Ma Xu
Abstract excerpt
Increasing evidence shows that single nucleotide polymorphisms (SNPs) or mutations in microRNAs (miRNAs) sequence may affect the processing and function of miRNAs and participate in the occurrence of diseases. Although many SNPs of miRNAs were found, their functions in the pathological process of nerve cells were only just emerging. In the present study, the effect of the SNP of one neuronal miRNA, miR-124, on...
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