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Article

Upregulated JAG1 Enhances Cell Proliferation in Adrenocortical Carcinoma

16 Mar 2012

Abstract excerpt

PURPOSE: The purpose of this study was to examine the expression and molecular significance of JAG1, a ligand for the Notch developmental signaling pathway, in adrenocortical carcinoma (ACC). EXPERIMENTAL DESIGN: Human microarray data were analyzed for genes expressing ligands for the Notch pathway and validated with quantitative real-time PCR (QPCR) and immunoblots of RNA and protein, respectively. ACC cells...

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PMID: 22427350
DOI: 10.1158/1078-0432.ccr-11-2371

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