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Review Paper: Origin and Molecular Pathology of Adrenocortical Neoplasms

1 Mar 2009

Abstract excerpt

Neoplastic adrenocortical lesions are common in humans and several species of domestic animals. Although there are unanswered questions about the origin and evolution of adrenocortical neoplasms, analysis of human tumor specimens and animal models indicates that adrenocortical tumorigenesis involves both genetic and epigenetic alterations. Chromosomal changes accumulate during tumor progression, and aberrant...

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PMID: 19261630
DOI: 10.1354/vp.46-2-194

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