Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of CFTR, SPINK1, PRSS1 and AAT mutations in children with acute or chronic pancreatitis.

Journal of pediatric gastroenterology and nutrition - 1 Sept 2006

Sobczyńska-Tomaszewska Agnieszka, Bak Daniel, Oralewska Beata, Oracz Grzegorz, Norek Aleksandra, Czerska Kamila, Mazurczak Tadeusz, Teisseyre Mikołaj, Socha Jerzy, Zagulski Marek, Bal Jerzy

Abstract excerpt

OBJECTIVES: Defects of PRSS1, SPINK1, CFTR and AAT are considered causative or predisposing to pancreatitis. The aim of this study was to evaluate the impact of these defects into molecular pathology of chronic pancreatitis (CP) and acute recurrent pancreatitis (ARP). METHODS: Ninety-two children with CP or ARP, 55 family members and 50 controls were investigated. The subjects were screened for PRSS1 mutations:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Disease
Share to alpha 1-Antitrypsin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chronic Disease

Share to Cystic Fibrosis Transmembrane Conductance Regulator

Share to Pancreatitis

Share to Trypsin

Share to Trypsin Inhibitor, Kazal Pancreatic

Share to Trypsinogen

Source

Identifiers

PMID: 16954950
DOI: 10.1097/01.mpg.0000232570.48773.df

Genes

CFTR
PRSS1
SPINK1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of CFTR, SPINK1, PRSS1 and AAT mutations in children with acute or chronic pancreatitis.PMID 16954950Read ↗

Identification of CFTR, PRSS1, and SPINK1 mutations in 381 patients with pancreatitis.Semantic proximity Read ↗

Genetic Mutations in Pediatric Pancreatitis.Semantic proximity Read ↗

CFTR, SPINK1, CTRC and PRSS1 variants in chronic pancreatitis: is the role of mutated CFTR overestimated?Semantic proximity Read ↗

Mutation analysis of PRSS1, SPINK1 and CFTR gene in patients with alcoholic and idiopathic chronic pancreatitis: A single center study.Semantic proximity Read ↗

Clinical and Morphological Characteristics of Sporadic Genetically Determined Pancreatitis as Compared to Idiopathic Pancreatitis: Higher Risk of Pancreatic Cancer in CFTR VariantsSemantic proximity Read ↗

Gene mutations in children with chronic pancreatitis.Semantic proximity Read ↗

CFTR, PRSS1 and SPINK1 mutations in the development of pancreatitis in Brazilian patients.Semantic proximity Read ↗

Complete cystic fibrosis transmembrane conductance regulator gene sequencing in patients with idiopathic chronic pancreatitis and controls.Semantic proximity Read ↗

CFTR and/or pancreatitis susceptibility genes mutations as risk factors of pancreatitis in cystic fibrosis patients?Semantic proximity Read ↗

Cystic fibrosis gene mutations and pancreatitis risk: relation to epithelial ion transport and trypsin inhibitor gene mutations.Semantic proximity Read ↗

Genetic mutations in SPINK1, CFTR, CTRC genes in acute pancreatitis.Semantic proximity Read ↗

Genophenotypic Analysis of Pediatric Patients With Acute Recurrent and Chronic Pancreatitis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.