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Article

Identification of CFTR, PRSS1, and SPINK1 mutations in 381 patients with pancreatitis.

Pancreas - 1 Oct 2006

Keiles Steven, Kammesheidt Anja

Abstract excerpt

OBJECTIVES: Chronic pancreatitis is a progressive inflammatory disorder leading to irreversible exocrine and/or endocrine impairment. It is well documented that mutations in the cationic trypsinogen (PRSS1) gene can cause hereditary pancreatitis. Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) and the serine protease inhibitor Kazal type 1 (SPINK1) genes are also associated with...

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Source

Identifiers

PMID: 17003641
DOI: 10.1097/01.mpa.0000232014.94974.75

Genes

CFTR
PRSS1
SPINK1

Variants

Provenance

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