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Article

Cellular characteristics of head and neck cancer stem cells in type IV collagen-coated adherent cultures.

Experimental cell research - 10 Jun 2012

Lim Young Chang, Oh Se-Yeong, Kim Hyunggee

Abstract excerpt

Although head and neck squamous carcinoma cancer stem cells (HNSC-CSCs) can be enriched in serum-free suspension cultures, it is difficult to stably expand HNSC-CSC lines in suspension due to spontaneous apoptosis and differentiation. Here, we investigated whether HNSC-CSCs can be expanded without loss of stem cell properties by adherent culture methods. Cell culture plates were coated with type IV collagen,...

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Identifiers

PMID: 22426199
DOI: 10.1016/j.yexcr.2012.02.038

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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