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Article

Nonadhesive Culture System as a Model of Rapid Sphere Formation with Cancer Stem Cell Properties

16 Feb 2012

Abstract excerpt

BACKGROUND: Cancer stem cells (CSCs) play an important role in tumor initiation, progression, and metastasis and are responsible for high therapeutic failure rates. Identification and characterization of CSC are crucial for facilitating the monitoring, therapy, or prevention of cancer. Great efforts have been paid to develop a more effective methodology. Nevertheless, the ideal model for CSC research is still...

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PMID: 22359637
DOI: 10.1371/journal.pone.0031864

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