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Article

Cancer stem cells are enriched in Fanconi anemia head and neck squamous cell carcinomas

26 Sept 2014

Abstract excerpt

Fanconi anemia (FA) patients have an increased risk of head and neck squamous cell carcinoma (HNSCC) at a higher rate with no apparent risk factors. HNSCC of FA patients is an aggressive tumor characterized by multifocal origin, early metastases and frequent recurrences. Given that cancer stem cells (CSC) drive tumorigenesis, tumor recurrence and metastasis, in this study, we characterized the CSC population in...

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PMID: 25340704
DOI: 10.3892/ijo.2014.2677

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