Article
Molecular genetic studies of gene identification for osteoporosis: the 2009 update.
Endocrine reviews - 1 Aug 2010
Xu Xiang-Hong, Dong Shan-Shan, Guo Yan, Yang Tie-Lin, Lei Shu-Feng, Papasian Christopher J, Zhao Ming, Deng Hong-Wen
Abstract excerpt
Osteoporosis is a complex human disease that results in increased susceptibility to fragility fractures. It can be phenotypically characterized using several traits, including bone mineral density, bone size, bone strength, and bone turnover markers. The identification of gene variants that contribute to osteoporosis phenotypes, or responses to therapy, can eventually help individualize the prognosis, treatment,...
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