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Article

Oxytocin gene polymorphisms influence human dopaminergic function in a sex-dependent manner.

Biological psychiatry - 1 Aug 2012

Love Tiffany M, Enoch Mary-Anne, Hodgkinson Colin A, Peciña Marta, Mickey Brian, Koeppe Robert A, Stohler Christian S, Goldman David, Zubieta Jon-Kar

Abstract excerpt

BACKGROUND: Oxytocin, classically involved in social and reproductive activities, is increasingly recognized as an antinociceptive and anxiolytic agent, effects which may be mediated via oxytocin's interactions with the dopamine system. Thus, genetic variation within the oxytocin gene (OXT) is likely to explain variability in dopamine-related stress responses. As such, we examined how OXT variation is associated...

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Identifiers

PMID: 22418012
DOI: 10.1016/j.biopsych.2012.01.033
PMCID: PMC3392442

Genes

OXT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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