Article
Association of matrix metalloproteinase-12 polymorphisms with chronic obstructive pulmonary disease risk: A protocol for systematic review and meta analysis.
Medicine - 31 Jul 2020
Yang Hongjing, Zhang Chuantao, Wu Jianying, Xiao Wei, Xie Xiaohong, Zeng Zhu, Chen Keling, Wang Wujun, An Xing, Tang Wenjun, Huang Qingsong
Abstract excerpt
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a multifactorial disease with gene-environment interaction leading to airflow limitation through the respiratory tract. Reports on the association of matrix metalloproteinase 12 (MMP-12) polymorphisms with COPD have been controversial. A new systematic evaluation which could examine whether MMP-12 mutations are associated with the susceptibility to COPD...
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