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Article

Genetic polymorphisms of matrix metalloproteinases and protein levels in chronic obstructive pulmonary disease in a Mexican population.

Biomarkers in medicine - 1 Jan 2015

Hernández-Montoya Jazmín, Pérez-Ramos Julia, Montaño Martha, Ramírez-Venegas Alejandra, Sansores Raúl H, Pérez-Rubio Gloria, Velázquez-Uncal Mónica, Camarena Angel, Ramos Carlos, Falfán-Valencia Ramcés

Abstract excerpt

AIM: To evaluate association of single nucleotide polymorphisms (SNPs) in the MMP1, MMP2, MMP9 and MMP12 genes and serum MMP-2 and MMP-9 levels in smoking chronic obstructive pulmonary disease (COPD) patients. MATERIALS & METHODS: Genotyping using real-time PCR in 330 smokers with COPD (COPD), 658 smokers without COPD (SNC) and 150 nonsmokers (NCNS), the analysis of samples used was χ(2) test. Using ELISA, the...

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Source

Identifiers

PMID: 26439471
DOI: 10.2217/bmm.15.75

Genes

MMP1
MMP12
MMP2
MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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