Article
Associations between XRCC1-Arg399Gln polymorphism and the risk of prostate cancer: an updated meta-analysis.
Amino acids - 18 Sept 2025
Deng Jiang, Xu Lihua, Zhou Jun, Huang He
Abstract excerpt
The X-ray repair cross-complementary group 1 (XRCC1) gene 399 codon polymorphism may alter the structure of DNA repair enzymes to regulate DNA repair capacity. Impaired DNA repair ability can lead to the development of cancers such as prostate cancer (PCa). Although the association between the XRCC1 codon 399 polymorphism and the risk of PCa has been widely reported, the results have not been clear. Data were...
Read the complete abstract on PubMedTopics
- Humans
- X-ray Repair Cross Complementing Protein 1
- Male
- Prostatic Neoplasms
- Genetic Predisposition to Disease
- Polymorphism, Single Nucleotide