Article
Neural-differentiated mesenchymal stem cells incorporated into muscle stuffed vein scaffold forms a stable living nerve conduit.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Oct 2012
Hassan Nur Hidayah, Sulong Ahmad Fadzli, Ng Min-Hwei, Htwe Ohnmar, Idrus Ruszymah B H, Roohi Sharifah, Naicker Amaramalar S, Abdullah Shalimar
Abstract excerpt
Autologous nerve grafts to bridge nerve gaps have donor site morbidity and possible neuroma formation resulting in development of various methods of bridging nerve gaps without using autologous nerve grafts. We have fabricated an acellular muscle stuffed vein seeded with differentiated mesenchymal stem cells (MSCs) as a substitute for nerve autografts. Human vein and muscle were both decellularized by liquid...
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