Article
Undifferentiated and differentiated adipose-derived stem cells improve nerve regeneration in a rat model of facial nerve defect.
Journal of tissue engineering and regenerative medicine - 1 Feb 2017
Watanabe Yorikatsu, Sasaki Ryo, Matsumine Hajime, Yamato Masayuki, Okano Teruo
Abstract excerpt
Autologous nerve grafting is the current procedure used for repairing facial nerve gaps. As an alternative to this method, tissue engineering cell-based therapy using induced pluripotent stem cells, Schwann cells and bone marrow-derived mesenchymal stem cells has been proposed. However, these cells have major problems, including tumorigenesis in induced pluripotent stem cells and invasiveness and limited tissue...
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