Article
Cardiolipin synthase is required for Streptomyces coelicolor morphogenesis.
Molecular microbiology - 1 Apr 2012
Jyothikumar Vinod, Klanbut Khanungkan, Tiong John, Roxburgh James S, Hunter Iain S, Smith Terry K, Herron Paul R
Abstract excerpt
The fluid mosaic model has recently been amended to account for the existence of membrane domains enriched in certain phospholipids. In rod-shaped bacteria, the anionic phospholipid cardiolipin is enriched at the cell poles but its role in the morphogenesis of the filamentous bacterium Streptomyces coelicolor is unknown. It was impossible to delete clsA (cardiolipin synthase; SCO1389) unless complemented by a...
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